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| “形-精-气-神”模式中“神”的胚胎学佐证 --从先天元神到后天识神的发育时序阐释 |
| Embryological Evidence for "Shen" in the medical model of "Xing-Jing-Qi-Shen" : An Interpretation of the Developmental Sequence from Innate Yuan Shen to Acquired Shi Shen |
| 投稿时间：2026-03-16 修订日期：2026-03-16 |
| 中文关键词: 神 元神 识神 胚胎发育 神经嵴细胞 形-精-气-神 医学模式 |
| 英文关键词: Shen Yuan Shen Shi Shen embryonic development neural crest cells Xing-Jing-Qi-Shen medical model |
| 基金项目:浙江中医药大学附属医院科研专项关于 “形-精-气-神”医学模式理论探索,编号:2023FSYYZX44 |
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| 中文摘要: |
| <br /> “神”作为“形-精-气-神”医学模式中的一环,其现代科学内涵亟待深入阐释。本文基于中医“元神”(先天之神)与“识神”(后天之神)的理论划分,将受精卵蕴含DNA的结构框架实作“元神”的载体,其遗传特性与表观遗传信息视作元神,将发育成熟后的大脑神经网络结构视作“元神”作用体现和“识神”的载体,其功能视作识神为主。本文从三个层面论证了这一假说:①胚胎早期神经系统的率先奠基与神经嵴细胞的全身布散,印证了“神为生命之主宰”的先导性与统摄性；②脑髓与脏腑在形态构建期的并行发育与预先连接,展示了“形神合一、互为其根”的动态构建逻辑；③脏腑功能的先行成熟与脑髓功能的后成统御,阐释了“先天为体、后天为用”的终极实现。研究表明,从神经管形成到神经嵴迁移,从脏腑成形到神经网络精细化,胚胎发育的全过程正是单个人体的“神”从无形的蕴含“信息”演化为有形之功能的现代生物学表达。这一汇通为“形-精-气-神”模式的建构奠定了发生学基础。 |
| 英文摘要: |
| "Shen" (Spirit), as an integral component of the medical model of “Xing-Jing-Qi-Shen" (Body-Essence-Qi-Spirit), requires in-depth elucidation of its modern scientific implications. Based on the theoretical distinction in traditional Chinese medicine between “Yuan Shen” (innate spirit) and “Shi Shen” (acquired spirit), this paper proposes that the structural framework of DNA contained in the fertilized egg serves as the carrier of “Yuan Shen”, with its genetic and epigenetic information regarded as “Yuan Shen” itself. Meanwhile, the neural network in the developed brain is considered both a manifestation of “Yuan Shen” and a carrier of “Shi Shen,” with its functions primarily attributed to “Shi Shen”. This hypothesis is demonstrated from three perspectives: (1) The early establishment of the nervous system during embryonic development and the distribution of neural crest cells throughout the body confirm the pioneering and governing role of "Spirit as the master of life." (2) The parallel development and pre-established connections between the brain and the viscera during morphogenesis illustrate the dynamic logic of "unity of body and spirit, mutual rooting of each other." (3) The earlier maturation of visceral functions and the later dominance of brain functions explain the ultimate realization of "innate nature as the foundation, acquired nature as the function." Studies have shown that from neural tube formation to neural crest migration, and from visceral morphogenesis to neural network refinement, the entire process of embryonic development represents the modern biological expression of how an individual''s “Shen" (Spirit) evolves from an intangible "information" into tangible functions. This integration lays the embryological groundwork for the "Xing-Jing-Qi-Shen" medical model. |
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